This little black bottle packs a wallop of greatness.
I’m an unapologetic skincare junkie. I’ve tried the serums, I’ve done the research, I’ve spent the money — and I’ve learned some expensive lessons along the way. So when I tell you that the Medik8 Liquid Peptides Advanced MP is my go-to peptide serum by far, I want you to know that statement comes with receipts.
I discovered it thanks to Dr. Ekta on TikTok — and my skin has never been the same. Three months in, I’m still on my first bottle, my skin is firmer and smoother, and I have zero plans to ever go back to anything else. This is my honest review.
Why I Chose the Advanced MP
Medik8 makes two versions of Liquid Peptides — the original and the Advanced MP. I went straight for the Advanced MP for two very specific reasons:
- More peptides. The Advanced MP contains 13 age-defying peptides at 30% versus 10 in the original. More peptides, more results. Simple math.
- Growth factors. The Advanced MP contains Dual MiniProteins™ — a breakthrough technology that combines the deep penetration of peptides with the enhanced potency of proteins. Growth factors signal your skin to repair, regenerate, and produce collagen. For a serious skin signaling night routine, this is non-negotiable.
If you’re going to invest in a peptide serum, invest in the one that does more. That’s my philosophy and I’m sticking to it.
What’s Actually In It
The Medik8 Liquid Peptides Advanced MP is powered by:
- 30% Multi-Peptide Complex — 13 age-defying peptides working in concert to visibly smooth, firm and restore skin’s youthful texture
- Dual MiniProteins™ — GF MiniProtein™ activates skin regeneration and Expression Line MiniProtein™ relaxes and smooths dynamic expression lines
- Micro-encapsulated Hyaluronic Acid — penetrates deeply to expand within wrinkles and visibly plump fine lines
- Drone-targeted technology — delivers each peptide exactly where it’s needed most in the skin for maximum visible results
It’s also clinically proven to diminish the appearance of expression lines in 10 minutes and deep-set wrinkles in 8 weeks. Independent clinical study. Real results. Not marketing fluff.
How I Use It
The Medik8 Liquid Peptides Advanced MP is a key player in my skin signaling nights — twice a week, both nights following my tretinoin nights. Here’s exactly where it sits in my routine:
- Double cleanse
- Reedle Shot 700 Spicules (Night 1 only)
- Dermaline Bio Activing PDRN Ampoule
- Peach & Lily Miniprotein Exosome Bioactive Ampoule
- Medik8 Liquid Peptides Advanced MP ✔️ ← RIGHT HERE
- Tatcha Indigo Overnight Repair (moisturizer)
I also use a separate copper peptide — The Ordinary’s copper peptide serum — in my morning routine, specifically the morning after tret nights. Copper peptides are incredible for wound repair and help counteract the harshness that tretinoin can cause. I intentionally keep my peptides separated — growth factors and signaling peptides at night, copper peptides in the morning. Your skin will thank you.
⚠️ Important heads up: Skip this one in the mornings if you wear makeup. It can pill under foundation and nobody has time for that. Nighttime only for this girl!
How It Compares
I’ve tried other peptide serums. I’ll be honest about that.
The DRMTLGY Needle-less Serum and their Peptide Night Cream are sitting on my shelf right now. I’m using them up because I’m not a person who wastes products — but I won’t be repurchasing. I tried a few Lancôme serums too. Spendy and I didn’t see much change. Expensive lessons, but lessons learned.
The Medik8 Liquid Peptides Advanced MP is in a completely different league. The growth factors, the drone-targeted technology, the 13 peptide complex — this is formulated by serious scientists for serious results. And at 55, serious results are exactly what I’m after.
The Texture and Experience
Crystal clear. Lightweight. Silky smooth going on. It sinks into the skin effortlessly and I love the way it feels as I massage it in. A little goes a long way — I’m still on my first bottle after three months which makes that $94 price tag feel considerably more reasonable.
Skin signaling nights are by far the most expensive nights of my skincare week. But I didn’t build this routine all at once — little by little I added products to my repertoire as my budget allowed. If you’re just starting out, the Medik8 Liquid Peptides Advanced MP is absolutely worth making your first serious investment.
My Honest Results
Three months in:
- Firmer skin overall
- Noticeably smoother texture
- Visible reduction in fine lines as part of my complete skin signaling routine
Would I repurchase? Without hesitation. When this bottle runs out — and it’s going to be a while because a little goes a long way — I’m buying another one immediately. This little black bottle packs a wallop of greatness. That’s all I need to say.
The Bottom Line
At $94 the Medik8 Liquid Peptides Advanced MP is an investment. But for a serious skincare junkie who understands the science of skin signaling, growth factors, and peptide technology — it’s worth every single penny. I’m 55, I’m glowing, and this little black bottle is a big reason why.
There’s no place like great skin. 🌈
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